Background: Aldosterone-producing adrenocortical adenoma (APA) is responsible for the majority of cases clinically diagnosed as primary aldosteronism.Aldosterone synthase (CYP11B2) is one of the enzymes that play essential roles in aldosterone synthesis and is involved in the pathogenesis of primary aldosteronism.Recent studies have demonstrated th
Presence of intraoral pathology poses a great challenge during management of pediatric airway.We report management of big intraoral cystic color touch 7/97 swelling physically occupying the entire oral cavity restricting access to airway.Preintubation aspiration of swelling was done to decrease its size and make room for airway manipulation, follow
Background: Most cases of hemifacial spasm result from mechanical compression at the root exit zone of the facial nerve by vascular loops, and only a few cases are caused by vestibular schwannoma.Case presentation: We report a case of symptomatic hemifacial spasm induced by a small vestibular schwannoma that was totally resected.A 64-year-old man w
Genetic robustness is the ability of a genome to incorporate mutations with the result of no fitness changes.Thus, more robust viruses have an honeywell df300 n95 increased neutral mutation rate.This property is particularly important in RNA viruses due to their high mutation rates.The most direct way of measuring robustness in vesicular stomatitis
Shigella flexneri, the pathogen responsible for bacillary dysentery, has evolved multiple strategies to control the inflammatory response.Here, we show that Shigella subverts the subcellular trafficking of the intercellular adhesion molecule-1 (ICAM-1), a key molecule in immune cell recruitment, essie sleigh it in a mechanism dependent on the injec